GENTIOPICROSIDE IMPROVES HIGH-FAT DIET-INDUCED NAFLD IN ASSOCIATION WITH MODULATION OF HOST SERUM METABOLOME AND GUT MICROBIOME IN MICE

Gentiopicroside improves high-fat diet-induced NAFLD in association with modulation of host serum metabolome and gut microbiome in mice

ObjectiveThe incidence of non-alcoholic fatty liver disease is increasing every year, and there is growing evidence that metabolites and intestinal bacteria play a causal role in NAFLD.Gentiopicroside, a major iridoids compound in gentian, has been reported to reduce hepatic lipid accumulation.However to date, no studies have confirmed whether the

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Mantaray modified multi-objective Harris hawk optimization algorithm expedites optimal load balancing in cloud computing

Task scheduling in the cloud is a difficult optimization challenge.The cloud system is assigned with a specific load based on the cloud architecture and user demands.However, both underloaded and overloaded situations result in a variety of system failures in terms of power consumption, machine failure, and so on.As a result, task-load balancing co

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